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Newsflash

Supported by the British Council, an obstetrician from Havana, Dr Davide Casagrandi Casanova, has visited the SAFE Warwick Lab for three weeks to learn from their experience in NIPD technology. Dr Casagrandi, who has an MSc in Prenatal Genetics and Fetal Medicine, aims to set up a new clinical service in Cuba. In the first instance this will concern NIPD of fetal genetic sex with special reference to conditions such as Duchenne Muscular Dystrophy and Congenital Adrenogenital Hyperplasia.
Created: 22/06/07, By: Olivia A Willcocks

Seventh QF-PCR Workshop

A three day QF-PCR course will take place from Friday 23rd to Sunday 25th November 2007 at General Lab in Quiron Hospital Madrid, Spain. Lectures and practical demonstrations are planned to cover all aspects of the QF-PCR procedures with particular emphasis to the analysis troubleshooting. Relevant literature will also be provided to the participants. The Course will be limited to 30 scientists already conversant with conventional PCR assays.
Created: 13/06/07, By: Olivia A Willcocks

Preterm Labour Workshop

A special issue of BMC Pregnancy & Childbirth with the title "Proceedings of the First and Second European Workshops on Preterm Labour of the Special Non-Invasive Advances in Fetal and Neonatal Evaluation (SAFE) Network of Excellence" has been published. This special issue comprises sixteen fully peer reviewed papers presented at the 1st and 2nd European Workshops on Preterm Labour, held on 22 June 2005 and 21–22 September 2006 in Tarragona. The special issue is openly accessible. The url is http://www.biomedcentral.com/1471-2393/7?issue=S1
Created: 11/06/07, By: Olivia A Willcocks

Patient Leaflets

Following discussion between the two laboratories offering NIPD for fetal sexing to high risk families in England, a patient information leaflet has been written. We hope that this will be useful for both health professionals and families. SAFE also hopes to translate this into a number of other languages with help of SAFE partners worldwide.
Created: 04/06/07, By: Olivia A Willcocks

Standardisation Workshop presentations now online

On March 7th-8th Tobias Legler hosted the SAFE workshop on Standardisation of NIPD for RhD and possibilities for CE-marking in Göttingen, Germany. The requirements for the large-scale implementation of the determination the foetal D-status from maternal plasma for decision making on Rh-prophylaxis in D-negative pregnant women were discussed. The presentations are now available in the Meetings area of this website.
Created: 28/03/07, By: Olivia A Willcocks

Revised edition of SAFE Newsletter

The revised edition of the SAFE Project newsletter is now available on the website.
Created: 16/03/07, By: Olivia A Willcocks

Recent developments in the non-invasive detection of Down's syndrome

Two recent high-profile scientific publications in Nature Medicine (Lo et al. 2007) and The Lancet (Dhallan et al. 2007), both accompanied by numerous reports in the lay media, have fostered hopes that it may very soon be possible to detect trisomy 21 (three copies of chromosome 21 leading to Down syndrome) non-invasively in the near future. Of interest is that both these approaches have utilized cell-free fetal nucleic acids and the analysis of single nucleotide polymorphism (SNPs). It is, however, noteworthy that they have chosen very different strategies.
Created: 01/03/07, By: Sinuhe Hahn

Visit to Dennis Lo’s Laboratory in Hong Kong

I was fortunate to be able to visit Dennis Lo’s laboratory at the Prince of Wales Hospital in Hong Kong in January of 2007. Dennis Lo’s laboratory discovered the presence cell-free fetal DNA in the plasma of pregnant women in 1997 using a non-invasive test involving real time PCR analysis and a Y chromosome specific sequence, SRY, to detect male fetuses. His laboratory is at the forefront of research into cell-free DNA analysis and is therefore a very exciting laboratory to be able to visit.
Created: 26/01/07, By: Cathy Meaney, Clinical Scientist, Regional Molecular Genetics, GOSH

£100,000 award goes to tiny charity with huge aims

Congratulations to SAFE partner Unique for receiving the most public votes to win the top prize of £100,000 in the DailyMail/RBS Children’s Charity Awards! Beverly Searle, Chief Executive Officer of Unique, said, "This is a wonderful achievement for a charity as small as ours, not least because most of the other finalists were major, well known charities.  It has also been an excellent opportunity to raise awareness of rare chromosome disorders and genetics among the general public." Click here to download Unique’s press release
Created: 25/01/07, By: Barry Yau

SoE activities at international conferences

The SAFE spreading of excellence team (SoE) based at University College London (UCL) attended the International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) world congress in London during September. The team promoted SAFE and recruited other units to join the collaborative study based at UCL. An abstract was also submitted by the group which detailed a reduction in amniocentesis and CVS when non-invasive fetal sexing was utilised in pregnancies at an increased risk of X-linked genetic disease and Congenital Adrenal Hyperplasia (CAH). Click here to see the abstract, which won the poster prize in its section. The SoE team also recently attended the annual conference of the British Society for Human Genetics in York, which was attended by 800 delegates. The SAFE information leaflet was put in every delegate pack, along side a letter inviting regional genetics units to participate in the collaborative study to bank samples based at UCL. There were reports in several national and one local newspaper and BBC on-line

Lyn Chitty has issued two reports from that conferences:

International Society of Ultrasound in Obstetrics and Gynecology Report
British Society for Human Genetics Report
Created: 28/09/06, By: Barry Yau - Project Manager

Fetal sexing: Global Perspectives on Practices, Ethics and Policy edited by Lyn Chitty and Theresa Marteau has just been published.

Wiley put out a news alert in association with its publication. This special issue arose from a SAFE workshop organised by Theresa last year and highlights some of the ethical issues raised by non-invasive prenatal diagnosis.

Click here to read the content list
Created: 01/08/06, By: Lyn Chitty

Consolidated EC Review report for year 2

The EC has released to SAFE its Consolidated review report for year 2. All SAFE partners have received by email the report. The reports are also available for downloading in the consortium area. In the consortium area menu click “EC Reports”, then scroll down to “EC Consolidated Review Report” to download the report.
Created: 01/08/06, By: Barry Yau - Project Manager

Invitation to become SAFE Associate

Invitations are called for from individuals or institutions to become a SAFE Associate if they are interested in the goals or technology areas of the SAFE Network. Click here to read the Terms of Association.
Created: 06/06/06, By: Barry Yau - Project Manager

Archive News:

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SAFE NIPD Workshop at the ESHG 2006 meeting in Amsterdam.

Following requests from colleagues attending this Workshop we have summarised the talks and included the Power Point presentations, starting with the session on RhD

Created: 29/08/06 By: Maj Hulten

New SAFE Fellow biography for Julie Hogg

Julie Hogg is a graduate of the University of Hertfordshire, where she studied Adult Nursing and Midwifery. She has developed a special interest in counselling and pre-natal diagnosis and is based in the Fetal Medicine Unit at University College Hospital, London. Julie is involved in SAFE as a research midwife, and is a member of work package 3 and facilitates data collection for work package 7.

Created: 28/07/06 By: Barry Yau - Project Manager

PhD Workshop presentations

Presentations from the PhD Workshop held in Zandvoort in May this year can be downloaded from the consortium area. After you enter the consortium area, click on the left menu “Workshops”, then click “2006” → “Induction Workshop for PhD students, Zandvoort, The Netherlands, 10th – 11th May 2006” → “Presentations”.

Created: 24/07/06 By: Barry Yau - Project Manager

SAFE protocol: Purification of free fetal DNA from maternal plasma with QIAamp DSP Virus Kit

This SAFE protocol by Sina Muller (UKG-GOE) can be downloaded from the consortium area. After you enter the consortium area, click on the left menu “PhD Students” then click “Protocol"

Created: 24/07/06 By: Barry Yau - Project Manager

Research work: WP2 and 7

Research work from WP2 and 7 can be downloaded from the consortium area. After you enter the consortium area, click “Research Work”.

Created: 24/07/06 By: Barry Yau - Project Manager

New SAFE Fellow biography for Dr Evelyn Tait

Dr Evelyn Tait graduated in Molecular Biology from Edinburgh University in 1991, and her research since then has been predominantly in the field of genomics, working for 4 years on physically mapping the Human X-chromosome, then going on to physically characterise the genome Candida albicans genome, for which she got her PhD at Aberdeen University in 2002, and following that up with work on the European Drosophila Genome Project.

Created: 28/06/06 By: Barry Yau - Project Manager

New PhD Student biography for Eliza Papageorgiou

Eliza is of Greek-Cypriot descent and is a graduate of the Department of Biology at Athens University. Eliza continued her studies by obtaining a MSc in "Human Molecular Genetics" from the Faculty of Medicine at Imperial College, London.

Created: 27/06/06 By: Barry Yau - Project Manager

New PhD Student biography for Lucie Sedlackova

Lucie has a Master of Science in Biochemistry and Biotechnology from the Institute of Chemical Technology, Prague and is currently in her final year of her PhD studies in Professor Ilona Hromadnikova’s Group.

Created: 27/06/06 By: Barry Yau - Project Manager

New PhD Student biography for Denisa Zlacka

Denisa has a Master of Science in Biochemistry from Jozef Safarik University in Slovakia and is currently in her final year of her PhD studies in Professor Ilona Hromadnikova’s Group.

Created: 27/06/06 By: Barry Yau - Project Manager

Meeting of Association of European Commission Project Managers (UK)

In early June the SAFE Project Manager, Barry Yau, attended the second meeting of the Association of European Commission Project Managers (UK), hosted by Miriam Mendes, Network Administrator of another NoE, DC Thera.

Created: 14/06/06 By: Barry Yau - Project Manager

New SAFE Fellow biography for Francesco Crea

Francesco graduated from College of Notre Dame, California, USA and also has an MSc in Biochemical Engineering from The University of Birmingham, UK.

Created: 14/06/06 By: Barry Yau - Project Manager

New PhD student biography for Hien Nguyen Thi Thu

PhD student Hien Nguyen Thi Thu of Charles University Prague has a biography on the website.

Created: 14/06/06 By: Barry Yau - Project Manager

SAFE WP4 Workshop 'New Technologies for Non-invasive Prenatal Diagnosis of Haemoglobinopathies'

Held in Limassol, Cyprus on 9-10 June – Click here for a report from Ciara O’Sullivan.

Created: 12/06/06 By: Dr Ciara O’Sullivan

The SAFE NIPD workshop

The SAFE NIPD workshop organised by Maj Hultén, Ala Szczepura and Dennis Lo took place at the RAI Congress Center Amsterdam on Monday 8th May 2006 as part of the programme of the European Society of Human Genetics Annual Conference (http://www.eshg.org/eshg2006).

Created: 25/05/06 By: admin

PhD Students Forum

PhD Students FORUM IS NOW LIVE! Navigate to the PhD area to log in.

Created: 25/05/06 By: admin

2nd Annual Pre Term Labour Meeting

Click Here for Agenda, Registration form and Accommodation form

Created: 25/05/06 By: admin

The Annual Report

The Annual Report for year 2 and the JPA for M25 to 42 are now in the Consortium Area. of the website. The deliverables and milestones for each workpackage for M25 to 42 can Viewed Here

Created: 25/05/06 By: admin

SAFE in the press

Stan Urbaniak and the work of the SAFE project have recently been featured in two leading newspapers Read them Here

Created: 25/05/06 By: admin

SAFE fellows

Dr Sandra Majer, Dr Jorg Strutwolf, Aicha Ait Soussan and Dr Chinnapapagari Satheesh Kumar Reddy, and the following PhD students Charlene Porter and Thomas Kroneis now have Bio's on the website.

Created: 25/05/06 By: admin


SAFE Non-invasive Prenatal Diagnosis Workshop at ESHG 8th May 2006 - Programme now available! Click Here For More Information

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New Technologies for Non-invasive Prenatal Diagnosis of Haemoglobinopathies Worshop Information 8th - 9th June Click Here For More Information

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IMSTAR Smart Imaging Systems, Learn More Here

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Partners: (16/03/06) can view all the activity bids for JPA 25 to 42 in the Consortium Area. The activity bids have been grouped in accordance with Workpackage, Spreading of Excellence and Intergration. Click Here

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SAFE MD Students: (03/03/06)Bio of Sina Mueller has been added to the PhD & MD page Here her Here

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Meeting of FP6 Network of Excellence Administrators Click here for more Information

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New SAFE Fellow: (23/02/06)Welcome to Amelia Hollywood Meet Her Here

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Induction Workshop for PhD students May 2006, The Netherlands. Details Now available Click Here

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SAFE WP4 Workshop 'Advances in Neonatal Screening', 5th - 6th October 2006, Copenhagen, Denmark Navigate to the Event

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SAFE WP4 Workshop 'New Technologies for Non-invasive Prenatal Diagnosis of Haemoglobinopathies', 9-10 June, 2006, Nicosia, Cyprus. Navigate to the Event

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SAFE WP4 2nd Annual Meeting on 'Pre-term Labour', 21-22 September, 2006, Tarragona, Spain. Navigate to the Event

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Newsflash: Missing Girls of India Navigate to the Story

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Welcome to Gerasimos Dimisianos, a PhD student appointed under a SAFE PhD Bursary awarded to Dr Ariadni Mavrou of Athens University School of Medicine. Meet him here

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Welcome to Floriana Della Ragione, a PhD student appointed under a SAFE PhD Bursary awarded to Dr Maurizio D’Esposito of the Institute of Genetics and Biophysics, Italy. Meet her here

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Welcome to Thessalia Papasavva, a PhD student appointed under a SAFE PhD Bursary awarded to Dr Marina Kleanthous, Senior Molecular Geneticist at The Cyprus Institute of Neurology and Genetics. Meet her here

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Welcome to William Puszyk, a PhD student appointed under a SAFE PhD Bursary awarded to Professor Maj Hulten, Department of Biological Sciences, University of Warwick. Meet him here

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SAFE General Assembly 2006 agenda now available on the website Click Here

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Advice from the SAFE Consortium with regards the Baby Gender Mentor Test Read the statement

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Mr Barry Yau starts work as the SAFE Project Manager Read More

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In October 2005 Dr. Ilona Hromadnikova, PhD. (Partner 10), was announced Associate Professor for Immunology. Read More

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In May 2005 Dr. Tobias J. Legler (Partner 29) was announced Associate Professor for Transfusion Medicine. Read More

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SEQUENOM Secures Rights to Key Non-Invasive Prenatal Diagnostic Intellectual Property.
Read this news release on PR News Wire: 20th October 2005.

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Visit the new and improved Workpackage 6 Areawhere you can meet the team and learn more about their research.

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Hot off the Press! More New journals on Non Invasive PreNatal diagnosis available in the Journal Club

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Photos and Presentations from recent meetings are now available on the website in the Meetings Archive Area

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